Research

 

IMM is dedicated to mechanistic studies of basic biological processes as well as disease-related topics.

 

Research

IMM is dedicated to mechanistic studies of basic biological processes as well as disease-related topics. This includes, but is not limited to, gene expression and function, organism development, nucleic acid biology, immunity, vesicular trafficking and membrane dynamics, neuroscience, behavior and stress response. We use a wide range of model systems, such as cell culture, yeast, worm, fly, mouse and patient samples, complemented by cutting-edge molecular biology, cell biology and imaging technology. Among research by primary faculty members, Dr. Fang-Jen Lee and Dr. Ya-Wen Liu focus on studying the molecular basis that regulates the dynamics of biological membrane and membrane-bound organelles. Dr. Zee-Fen Chang is an expert of nucleic acid metabolism and DNA repair. Dr. Chun-Liang Pan studies the neural and circuit basis of behavior and how stress responses contribute to behavioral plasticity. Dr. Li-Chung Hsu studies innate immunity and the mechanisms of inflammation. Dr. Hsiu-Hsiang Lee works on neural development in the fruit fly. Dr. Hsin-Yue Tsai investigates how small RNAs are involved in the regulation of animal physiology. These researches culminate in publications in top journals, such as Neuron, PNAS, Developmental Cell, Nature Communications, Journal of Cell Biology, Development and PLOS Genetics.